Lou Gehrig, the Yank's great first baseman and the son of poor immigrants, rose to heights of baseball fame -- only to be cut down at the peak of his career by an incurable disease known as ALS.

Traces the life of Lou Gehrig, famous baseball Hall of Fame player who played in 2130 consecutive games before falling at age 37 to ALS, a deadly nerve disease which now bears his name. Gehrig is followed from his athletic childhood in New York to his famous 'Luckiest Man' speech at his farewell day in 1939.