A young boy and his Norwegian grandmother, who is an expert on witches, together foil a witches' plot to destroy the world's children by turning them into mice.

Nine-year-old Luke finds that saving the world from witches is a tall order for a boy who has been turned into a mouse.

The tale of a young orphaned boy who, in late 1967, goes to live with his loving Grandma in the rural Alabama town of Demopolis. As the boy and his grandmother encounter some deceptively glamorous but thoroughly diabolical witches, she wisely whisks him away to a seaside resort. Regrettably, they arrive at precisely the same time that the world's Grand High Witch has gathered her fellow cronies from around the globe, undercover, to carry out her nefarious plans.