Acknowledgment | p. xi |
Foreword | p. xiii |
A Patient's Perspective | p. xiii |
A Sister's Perspective | p. xvi |
The Nurses' Perspective | p. xxii |
Note from the Author | p. xxix |
Introduction | p. 1 |
Part 1 The Illness and Its Characteristics | p. 7 |
Questions 1-24 provide information for people who've just been diagnosed with schizophrenia or related disorders: |
1 What is schizophrenia? | p. 8 |
2 What are the first signs of this illness? How do I know whether someone has schizophrenia? | p. 14 |
3 Is being "schizophreniform" the same as having "schizophrenia"? | p. 22 |
4 What does it mean to have a "schizotypal personality disorder"? | p. 23 |
5 What is schizoaffective disorder? | p. 24 |
6 How is schizophrenia different from manic depression or bipolar disease? | p. 27 |
7 Is it possible to hear voices that are not there and not be ill? | p. 29 |
8 Does being told one has a psychosis mean one has schizophrenia? | p. 30 |
9 What is catatonia? | p. 31 |
10 What is a delusion? | p. 34 |
11 What is meant by positive and negative symptoms? | p. 36 |
12 Do people with schizophrenia have language problems? | p. 36 |
13 Do people with schizophrenia get depression? | p. 38 |
14 Are memory problems symptoms of schizophrenia? | p. 39 |
15 Do people with schizophrenia have a low IQ? | p. 40 |
16 Are muscular problems associated with schizophrenia? | p. 41 |
17 Do people with schizophrenia have a reduced life span or die from their illness? | p. 42 |
18 Are there medical conditions that look like schizophrenia? | p. 42 |
19 Do people with schizophrenia have fewer offspring? | p. 43 |
20 Do people diagnosed with a first episode of schizophrenia recover? If so, how long will this take? | p. 44 |
21 What is the course of chronic schizophrenia over time, and what can influence it? | p. 46 |
22 What can patients and their families do to minimize symptoms and influence outcome? | p. 48 |
23 What happens if someone opts for no treatment or gets the wrong treatment? | p. 49 |
24 Are there some societies in which no individuals develop schizophrenia? | p. 50 |
Part 2 Treatment: When, Where, by Whom, and With What? | p. 53 |
Questions 25-41 review different options available to treat schizophrenia: |
25 Who first sees an individual with schizophrenia, and what type of professional can treat the first symptoms? | p. 54 |
26 Why won't some psychiatrists treat people with schizophrenia? | p. 58 |
27 What if I do not have insurance or my policy does not cover psychiatric care? | p. 59 |
28 Do I have to be treated in a hospital if I have schizophrenia? If so, for how long? | p. 61 |
29 What treatments were used before pharmaceutical companies introduced neuroleptic medication? | p. 63 |
30 What are the current choices for medication? | p. 66 |
31 Are combinations of different medications more effective than one alone? | p. 71 |
32 When to use clozapine and if it doesn't work, then what? | p. 73 |
33 Are there any new possibilities for treatments on the horizon? | p. 75 |
34 What are the medication side effects and how are they resolved? | p. 76 |
35 How long does medication have to be taken? | p. 79 |
36 Are long-acting injectables more helpful than oral medications? | p. 80 |
37 Is electroconvulsive therapy (ECT) a treatment for schizophrenia? | p. 81 |
38 What is transcranial magnetic stimulation (TMS), and what can it do? | p. 82 |
39 What is cognitive behavioral therapy? | p. 83 |
40 Can a specific diet help, or using vitamin and fish oil supplements? | p. 85 |
41 Can individual, group, or family therapy help? | p. 89 |
Part 3 Genetic Risk | p. 91 |
Questions 42-57 discuss the genetic risks associated with schizophrenia: |
42 Is schizophrenia inherited? | p. 92 |
43 Should I adopt a baby whose birth parent had schizophrenia? | p. 95 |
44 If someone related to me has schizophrenia, what are my chances of getting it? What are the chances of my children getting schizophrenia if my partner has a relative with it as well? | p. 96 |
45 If I have an identical twin with schizophrenia, but I am well, what are my children's chances of having schizophrenia? | p. 97 |
46 What chromosomal risk factors can increase one's risk for schizophrenia? | p. 98 |
47 What are the methods used to find gene defects that are associated with schizophrenia? | p. 99 |
48 What genes are currently implicated as risks for schizophrenia? | p. 105 |
49 Are any risk genes specific to schizophrenia, or are they implicated in other diseases as well? | p. 107 |
50 How is it assumed that genes cause schizophrenia? | p. 107 |
51 What do DNA copy number variations (CNVs) have to do with schizophrenia? | p. 110 |
52 What is an endophenotype for schizophrenia? | p. 111 |
53 Are there lab tests to identify genetic risk for schizophrenia? | p. 113 |
54 Should I order commercially available DNA tests for schizophrenia? | p. 113 |
55 Can DNA testing enable physicians to determine which medications to administer? | p. 115 |
56 How can genetic research provide new treatments? | p. 116 |
57 What are the ethical concerns about genetic testing? Do those with genes for schizophrenia face discrimination? | p. 117 |
Part 4 Nongenetic Risk Factors | p. 121 |
Questions 58-64 discuss nongenetic-based risk factors that can contribute to schizophrenia: |
58 Do birth complications cause schizophrenia? | p. 122 |
59 Is schizophrenia more common in some cultural or racial groups than others? | p. 123 |
60 Can bad family relationships cause schizophrenia? | p. 124 |
61 Can immigration from another country increase risk for schizophrenia? | p. 126 |
62 Does where you live affect your risk for illness (urban versus rural environments)? | p. 127 |
63 Is schizophrenia infectious? | p. 127 |
64 Do viruses cause schizophrenia? | p. 128 |
Part 5 Substance Abuse and Schizophrenia | p. 131 |
Questions 65-71 review the effects of substance abuse in schizophrenia: |
65 Can the use of multiple street drugs in adolescence cause schizophrenia? | p. 132 |
66 Can cannabis/marijuana specifically cause schizophrenia? | p. 133 |
67 Can someone who has schizophrenia smoke cannabis/marijuana? Is it harmful, or can it also be beneficial? | p. 134 |
68 Which drugs cause schizophrenia-like symptoms in people who do not have schizophrenia? | p. 136 |
69 What does drug use do to people who have schizophrenia? | p. 136 |
70 Can someone who has schizophrenia drink alcohol? | p. 137 |
71 Why do people with schizophrenia smoke cigarettes excessively? | p. 137 |
Part 6 The Biology Underlying Schizophrenia: Current Research Findings | p. 139 |
Questions 72-79 provide information about the biologic findings on schizophrenia and testing being done to determine the disease's effects on the body: |
72 Are there any tests that can be taken from blood, urine, or spinal fluid to definitively diagnose schizophrenia? | p. 140 |
73 Is schizophrenia a "chemical imbalance"? | p. 141 |
74 Are there any differences in the brains of people who have schizophrenia? | p. 143 |
75 Should an MRI scan be performed? | p. 146 |
76 Are functional MRI scans useful? | p. 147 |
77 Should an EEG be done on patients with schizophrenia? | p. 148 |
78 When do the brain changes occur, and is schizophrenia considered a progressive brain disorder? | p. 149 |
79 Could the brain changes be due to an inflammatory process? | p. 152 |
Part 7 Violence and Aggression in Schizophrenia | p. 153 |
Questions 80-82 examine the connection between violent behavior and this mental illness: |
80 Do people with schizophrenia frequently commit violent acts and crimes? | p. 154 |
81 What should I do if my relative or friend is behaving violently or expressing violent thoughts? | p. 157 |
82 How can violent behavior be predicted? | p. 158 |
Part 8 Suicidal Behavior and Schizophrenia | p. 161 |
Questions 83-84 discuss how to best recognize someone at high risk for suicidal behaviors and prevent this tragic outcome: |
83 What are the signs of suicidal thoughts in schizophrenia? | p. 162 |
84 What can be done to prevent suicide attempts? | p. 164 |
Part 9 Issues for Women | p. 165 |
Questions 85-90 review specific issues unique to female patients with schizophrenia: |
85 Is schizophrenia different in women? | p. 166 |
86 Should patients who are pregnant take medication for schizophrenia? | p. 168 |
87 What is the risk of a postpartum relapse? | p. 169 |
88 Should mothers with schizophrenia breast-feed infants? | p. 170 |
89 Can estrogen for birth control help suppress symptoms? | p. 171 |
90 Can schizophrenia be exacerbated during and after menopause? | p. 171 |
Part 10 The Homeless and Schizophrenia | p. 173 |
Questions 91-92 discuss the connection between homelessness and mental illness: |
91 How prevalent is schizophrenia among the homeless? | p. 174 |
92 What causes homelessness, and what is being done to prevent it? | p. 176 |
Part 11 Legal and Ethical Issues | p. 181 |
Questions 93-95 discuss legal and ethical questions posed by schizophrenia: |
93 What does "involuntary" hospital commitment involve? | p. 182 |
94 What is the legal insanity defense? | p. 184 |
95 Why participate in research, and can patients with schizophrenia have the capacity to give informed consent for research and medical procedures? | p. 190 |
Part 12 Living with Schizophrenia and Recovery | p. 193 |
Questions 96-100 provide information on daily life with and recovery from schizophrenia: |
96 Can people with schizophrenia recover? | p. 194 |
97 What are the origins of the stigma attached to having schizophrenia? | p. 195 |
98 Can a person with schizophrenia be professionally creative? | p. 196 |
99 Should a person with schizophrenia drive a car? | p. 197 |
100 What support groups, books, and websites can I go to for help? | p. 199 |
Appendix: Resources | p. 201 |
Glossary | p. 211 |
Index | p. 221 |