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A Wall Street Journal 10 Best Nonfiction Book of the Year “Among a small cluster of very good recent books on cancer.” —The New York TimesPhiladelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research— the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute—with extensive original reporting, including more than thirty-five interviews—to the dozens of researchers, doctors, and patients with a direct role in this inspirational story.



About the Author

Jessica Wapner

Jessica Wapner is a freelance writer focused mainly on healthcare and medicine. Her work is published in The New York Times, Scientific American, Slate, Science, TheAtlantic.com, Nature Medicine, Ode, Psychology Today, and elsewhere. Her writing on cancer research and treatment also appears in the specialty magazines Oncology Business Review, Cure, and CR. Her blog, Work in Progress, is part of the PLoS Blog Network and focuses on the ethics and economics of drug development.Previously, she was the founding managing editor of two review journals, Clinical Advances in Hematology & Oncology and Gastroenterology & Hepatology, and also served as editor for Oncology Spectrum. She lives with her family in Beacon, NY.



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