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From a Pulitzer Prize-winning journalist and Los Angeles Times contributor, the untold story of how science went "big," built the bombs that helped win World War II, and became dependent on government and industry - and the forgotten genius who started it all, Ernest Lawrence.Since the 1930s, the scale of scientific endeavors has grown exponentially. Machines have become larger, ambitions bolder. The first particle accelerator cost less than one hundred dollars and could be held in its creator's palm, while its descendant, the Large Hadron Collider, cost ten billion dollars and is seventeen miles in circumference. Scientists have invented nuclear weapons, put a man on the moon, and examined nature at the subatomic scale - all through Big Science, the industrial-scale research paid for by governments and corporations that have driven the great scientific projects of our time.