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Ruth Zook returns home to Holmes County, Ohio, carrying a heavy suitcase and a heavier heart. Coerced into becoming a drug mule, Ruth retaliates by destroying her illicit burden and pays for it with her life. When Fannie Helmuth confesses that she was similarly coerced, Sheriff Bruce Robertson realizes that the drug dealers' operation reaches all the way to Florida's Pinecraft Amish community. He immediately moves the investigation South, where more innocent lives are in jeopardy.