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Making Nature is the first book to chronicle the foundation and development of Nature, one of the worlds most influential scientific institutions. Now nearing its hundred and fiftieth year of publication, Nature is the international benchmark for scientific publication. Its contributors include Charles Darwin, Ernest Rutherford, and Stephen Hawking, and it has published many of the most important discoveries in the history of science, including articles on the structure of DNA, the discovery of the neutron, the first cloning of a mammal, and the human genome. But how did Nature become such an essential institution? In Making Nature, Melinda Baldwin charts the rich history of this extraordinary publication from its foundation in 1869 to current debates about online publishing and open access.