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The general public has a glorified view of the pursuit of scientific research. However, the idealized perception of science as a rule-based, methodical system for accumulating facts could not be further from the truth. Modern science involves the idiosyncratic, often bumbling search for understanding in uncharted territories, full of wrong turns, false findings, and the occasional remarkable success. In his sequel to Ignorance (Oxford University Press, 2012) , Stuart Firestein shows us that the scientific enterprise is riddled with mistakes and errors - and that this is a good thing! Failure: Why Science Is So Successful delves into the origins of scientific research as a process that relies upon trial and error, one which inevitably results in a hefty dose of failure.