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One man. One love. One destiny. One thousand years . . . Hugh Jackman (Van Helsing, X-Men films) anchors acclaimed visionary filmmaker Darren Aronofsky's (Requiem for a Dream, Pi) epic sci-fi adventure chronicling a man's thousand-year struggle to save the woman he loves (Academy Award winner Rachel Weisz--The Constant Gardener) . Searching for the secrets of eternal life, he embarks on three parallel quests, in three lives, in three millennia, to unlock the mysteries of life that have consumed him for centuries.

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