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In Rebecca Miller's witty romantic comedy, Maggie (Greta Gerwig) is a vibrant New Yorker, who without success in finding love, decides to have a child on her own. But when she meets John Harding (Ethan Hawke) , an anthropology professor and struggling novelist, she falls in love for the first time. Complicating matters, John is in an unhappy marriage with Georgette (Julianne Moore) , an ambitious academic who is driven by her work. With some help from Maggie's eccentric best friends, married couple Tony (Bill Hader) and Felicia (Maya Rudolph) , Maggie sets in motion a new plan that intertwines their lives and connects them in surprising and humorous ways.